Directrices recientes recomiendan el tratamiento antihipertensivo para individuos prehipertensivos con presión arterial entre 130/80 y 139/89 mm Hg. Este estudio evalúa la rentabilidad de 3 intervenciones en adultos prehipertensivos chinos: sustitución de sal, tratamiento antihipertensivo de medicamentos y su combinación Ver más….
Asociación entre Factores de riesgo vascular en las edades medias de la vida e Incidencia de Demencia en la cohorte de Riesgo de Ateroesclerosis en la Comunidad (ARIC) Cohort.
¿Los factores de riesgo vasculares medidos en la edad media incrementan el riesgo de demencia en las etapas tardías de la vida? En este estudio de cohorte de 15 744 adultos negros y blancos fumadores de mediana edad, diabéticos, pre hipertensos e hipertensos se observó una asociación entre los factores de riesgo vasculares medidos en la edad media y el riesgo de demencia. Ver más….
Esta sección expone trabajos actuales, de carácter investigativo sobre la hipertensión arterial.
Serum C-reactive protein level and prehypertension in two Asian populations
Por: C Sabanayagam, A Shankar, J Lee, T Y Wong y E S Tai. Journal of Human Hypertension (2013) 27, 231–236.
Few previous studies in Western populations have reported an association between C-reactive protein (CRP) and prehypertension. However, no previous study has examined this association in Asians. We examined individuals who were free of hypertension from two independent population-based studies in Singapore: the Singapore Prospective Study Programme (SP2, n=2843 Chinese, Malay and Indians aged greater than or equal to24 years) and the Singapore Malay Eye Study (SiMES, n=957 Malays, aged 40–80 years). Prehypertension was defined as systolic blood pressure (BP) 120–139 mm Hg or diastolic BP 80–89 mm Hg. CRP was analyzed as categories (<1, 1–3, >3mgl). [Actualizado: 20 de marzo de 2013].
Por: S S Hassellund, S E Kjeldsen, I Seljeflot, A Karlsen y I Erlund y M Rostrup. Journal of Human Hypertension (2013) 27, 100–106.
High intake of fruits and vegetables is associated with reduced cardiovascular risk. A number of fruits and vegetables are rich in anthocyanins, which constitute a subgroup of the flavonoids. Anthocyanins have demonstrated anti-inflammatory and anti-oxidative properties, and anthocyanin-rich interventions have indicated beneficial effects on blood pressure and other cardiovascular risk factors. We assessed whether a purified anthocyanin supplement improves cardiovascular metabolic risk factors and markers of inflammation and oxidative stress in prehypertensive participants, and whether plasma polyphenols are increased following intake. [publicada: 25 enero de 2013
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Por: M Thoenes, D Spirk, M Böhm, F Mahfoud, L Thevathasan y P Bramlage. Journal of Human Hypertension (2013) 27, 131–137.
Hypertension in the elderly is a major risk factor for cardiovascular disease. We aimed to analyze determinants of blood pressure (BP) control across different age groups. Population of a large global survey on hypertension treatment and control including 18 927 patients was analyzed. A logistic regression analysis was conducted to estimate BP control rates and the prevalence of antihypertensive drug usage according to age. Systolic BP control decreased from 29.6% (95% confidence intervals (CI) 26.0;33.5) at 18–40 years to 22.4% (20.8;24.2) at >75 years (P<0.0001), and diastolic BP control increased from 31.6% (27.9;35.6) to 57.3% (55.2;59.3), respectively (P<0.0001). [publicada: 25 de enero 2013]
A manera de editorial. Los trabajos y opiniones que aquí se exponen son orientadores de lo que se publica en Cuba y en el mundo sobre aspectos relevantes de la hipertensión arterial.
Relationship between inflammation and microalbuminuria in prehypertension
Por: J F Navarro-González, C Mora, M Muros, J García, J Donate y V Cazaña. Journal of Human Hypertension (2013) 27,
119–125
Inflammation is a pathogenic factor for target-organ damage (TOD) in hypertension. This study examined the
relationship between inflammatory parameters and urinary albumin excretion (UAE) in prehypertension. A total of 65
prehypertensive subjects (blood pressure (BP) 120–139/80–89?mm?Hg) and 26 healthy volunteers with BP <120/80?mm?Hg were included. High-sensitivity C-reactive protein (hs-CRP), and serum and urinary tumor necrosis
factor-a (TNF-a) were measured as inflammatory markers. [publicada: 23 de enero 2013]
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