Por: Ihab Hajjar, Meaghan Hart, William Milberg, Vera Novak y Lewis Lipsitz.
The AVEC trial is the first study to explore impact of antihypertensives in those who are showing early evidence of cognitive difficulties that did not reach the threshold of dementia.
Success of this trial will offer new therapeutic application of antihypertensives that inhibit the renin angiotensin system and new insights in the role of this system in aging.
Pharmacotherapy for hypertension in the elderly
Por: Musini Vijaya M, Tejani Aaron M, Bassett Ken y Wright James M.
Cochrane Database of Systematic Reviews, Issue 01, 2012.
Treating healthy persons (60 years or older) with moderate to severe systolic and/or diastolic hypertension reduces all cause mortality and cardiovascular morbidity and mortality. The decrease in all cause mortality was limited to persons 60 to 80 years of age.
Re-examining the efficacy of b-blockers for the treatment of hypertension: a meta-analysis.
Por: Nadia Khan y Finlay A. McAlister. CMAJ, June 6, 2006, -174(12).
En un recientemente metanálisis publicado, investigadores afirmarón que los beta bloqueadores no deben utilizarse para tratar hipertensión, porque la fisiopatología de hipertensión difiere en pacientes mayores y más jovenes. Diseñamos este metaanálisis para aclarar la eficacia de los beta bloqueadores en los diferentes grupos etarios.
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