Reference frame for home pulse pressure based on cardiovascular risk in 6470 subjects from 5 populations

Los trabajos y opiniones que aquí se exponen son orientadores de lo que se publica en Cuba y en el mundo sobre aspectos relevantes de la hipertensión arterial.

Reference frame for home pulse pressure based on cardiovascular risk in 6470 subjects from 5 populations

Por: Lucas S Aparicio, Lutgarde Thijs, Kei Asayama, Jessica Barochiner, José Boggia, Yu-Mei Gu, Paula E Cuffaro1, Yan-Ping Liu, Teemu J Niiranen, Takayoshi Ohkubo, Jouni K Johansson, Masahiro Kikuya, Atsushi Hozawa8, Ichiro Tsuji, Yutaka Imai, Edgardo Sandoya, George S Stergiou, Gabriel D Waisman1 y  Jan A Staessen. Of the International Database on HOme blood pressure in relation to Cardiovascular Outcome (IDHOCO) Investigators.  Hypertension Research (2014) 37, 672–678.
The absence of an outcome-driven reference frame for self-measured pulse pressure (PP) limits its clinical applicability. In an attempt to derive an operational threshold for self-measured PP, we analyzed 6470 participants (mean age 59.3 years; 56.9% women; 22.5% on antihypertensive treatment) from 5 general population cohorts included in the International Database on HOme blood pressure in relation to Cardiovascular Outcome. During 8.3 years of follow-up (median), 294 cardiovascular deaths, 393 strokes and 336 cardiac events occurred. In 3285 younger subjects (<60 years), home PP only predicted all-cause and cardiovascular mortality (Pless than or equal to0.036), whereas in 3185 older subjects (greater than or equal to60 years) PP predicted total and cardiovascular mortality (Pless than or equal to0.0067) and all cardiovascular and coronary events (Pless than or equal to0.044).