Cardiovascular outcomes in the first trial of antihypertensive therapy guided by self-measured home blood pressure

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Cardiovascular outcomes in the first trial of antihypertensive therapy guided by self-measured home blood pressure

Por: Kei Asayama, Takayoshi Ohkubo, Hirohito Metoki, Taku Obara, Ryusuke Inoue, Masahiro Kikuya, Lutgarde Thijs, Jan A Staessen y Yutaka Imai. on behalf of Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP) investigators.  Hypertension Research (2012) 35, 1102–111.
Hypertension guidelines recommend blood pressure self-measurement at home (HBP), but no previous trial has assessed cardiovascular outcomes in hypertensive patients treated according to HBP. The multicenter Hypertension.
Treatment Based on Measurement by Electrical Devices of Blood Pressure (HOMED-BP; 2001–2010) trial involved 3518 patients (50% women; mean age 59.6 years) with an untreated systolic/diastolic HBP of 135–179/85–119 mm Hg. In a 2 × 3 design, patients were randomized to usual control (125–134/80–84mmHg (UC)) vs. tight control (<125/<80mmHg (TC)) of HBP and to initiation of drug treatment with angiotensin converting enzyme inhibitors, angiotensin receptor blockers or calcium channel blockers. [publicada 27 de noviembre de 2012.]