Investigaciones expone trabajos que pueden aún no tener evidencias suficientes por su actualidad.

Investigaciones expone trabajos que pueden aún no tener evidencias suficientes por su actualidad.

Synergism of irbesartan and amlodipine on hemodynamic amelioration and organ protection in spontaneously hypertensive rats

Por: Wen Shang, Ping Han, Cheng-bing Yang, Xiao-wen Gu, Wei Zhang, Li-ping Xu, Shou-ting Fu, Ding-feng Su y He-hui Xie. 

To investigate the synergism of low-doses of amlodipine and irbesartan on reduction of blood pressure variability (BPV), amelioration of baroreflex sensitivity (BRS) and organ protection in spontaneously hypertensive rats (SHR).
Long-term treatment with a combination of low-doses of amlodipine and irbesartan showed significant synergism on reduction of BP and BPV, restoration of BRS and organ protection in SHR. Besides BP reduction, the enhancement of BRS and reduction of BPV might contribute to the organ protectio