Common Variants in Epithelial Sodium Channel Genes Contribute to Salt Sensitivity of Blood Pressure The GenSalt Study

Common Variants in Epithelial Sodium Channel Genes Contribute to Salt Sensitivity of Blood Pressure The GenSalt Study.pdf

Por: Qi Zhao, MD, PhD, Dongfeng Gu, MD, PhD, James E. Hixson, PhD, De-Pei Liu, PhD,  Dabeeru C. Rao, PhD, Cashell E. Jaquish, PhD, et, al.  y for the Genetic Epidemiology Network of Salt Sensitivity Collaborative.   Common Variants in Epithelial Sodium Channel Genes Contribute to Salt Sensitivity of Blood Pressure The GenSalt Study.pdf

Rare mutations of the epithelial sodium channel (ENaC) lead to mendelian forms of salt-sensitive hypertension or salt-wasting hypotension. We aimed to examine the association between common variants in the ENaC genes and salt sensitivity of blood pressure (BP).