Can we study the baroreflex mechanisms with other variables than blood pressure and heart rate?
Por: Bruno Estañol. Archivos de Cardiología de México, vol. 82. núm. 02, abril – junio, 2012.
The baroreflex (BR) is a fundamental physiological mechanism that keeps the blood pressure (BP) stable by buffering the disturbances that arise in the system during the activities of the daily life.1 These disturbances alter the control system and deviate the mean BP either increasing or decreasing it. The BP is maintained tonically around a “set point” and the disturbances oscillate around it; they me be profound or relatively minor. Sometimes the disturbances occur at predictable times such as those seen during non-Rem sleep or rhythmic breathing. The disturbances could be considered “phasic” changes that are randomly added or subtrac- ted to the tonically maintained set point. The set point is dynamic and changes according to the mean BP maintained during a determined period of time, computed, perhaps, in hours or days or even minutes.
Por: Fadi Hikmat y L J Appel. Journal of Human Hypertension (2014) 28, 170–175.
In the Dietary Approach to Stop Hypertension (DASH) trial, the DASH diet reduced blood pressure (BP) in a diverse sample of US adults. Subsequent analyses of this trial documented the efficacy of the DASH diet in several subgroups. Although subgroup analyses in individuals with metabolic syndrome (MS) have not been performed, the DASH diet has been recommended in MS patients. This paper is a subgroup analysis of the DASH trial, in which we examined the effect of study diets on BP in participants with and without MS.
CYP3A5 polymorphism, amlodipine and hypertension
Por: Y-P Zhang, X-C Zuo, Z-J Huang, J-J Cai, J Wen, D D Duan y H Yuan. Journal of Human Hypertension (2014) 28, 145–149.
As a major cardiovascular risk factor for stroke, coronary artery disease, heart failure and end-stage renal disease, hypertension affects approximately one billion people and causes large economic burden worldwide. Cytochrome P450 3A5 (CYP3A5), belonging to the CYP3A subfamily, has been implicated in the regulation of blood pressure and may serve as a potential risk factor for the development of hypertension. Increased CYP3A5 activity could cause sodium and water retention by affecting the metabolism of cortisol in the kidneys. Furthermore, polymorphic CYP3A5 genotypes have been shown to cause differences in blood pressure response to antihypertensive drugs.
En esta sección les exponemos algunos artículos publicados sobre la hipertensión arterial.
De la Revista: CorSalud
Consideraciones actuales acerca de la enfermedad hipertensiva del embarzo y el puerperio
Por: MSc. Dr. Alain Cruz Portelles, MSc. Dr. Idaer M. Batista Ojeda, Dr.C. Ernesto Medrano Montero y Dr. Alfredo Ledea Aguilera. CorSalud 2014 Ene-Mar; 6 (1).
Niveles de tratamiento y control del hipertensión arterial en el policlínico Turcios Lima
Por: Dr. Adrian A. Naranjo Domínguez, Dr. Ariel Amador González, Dr. Ángel Y. Rodríguez Navarro y Dr. Ronald Aroche Aportela. CorSalud 2012 Oct-Dic; 4 (4).
Dispersión de la onda P en niños hipertensos. su relación con el peso corporal
Por: MSc.Dr. Elibet Chávez González, Dr.C. Emilio González Rodríguez, MSc.Dra. María del Carmen Llanes Camacho, MSc.Dra. Merlin Garí Llanes, Dra. Julieta García Sáez, Dra. Elizabet Fernández Martínez, Yosvany García Nóbrega y Raimundo Carmona Puerta. CorSalud 2012 Oct-Dic; 4 (4)
Por: Dr. Yosit Ponce Gutiérrez y Dr. Arik Ponce Gutiérrez. CorSalud 2012 Oct-Dic;4(4).
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