25/10/2013

Clinical characteristics of patients with resistant hypertension: the RESIST-POL study.

oct 25th, 2013. En: Propuestas del editor.

Estudios importantes sobre hipertension arterial de Cuba y el mundo

Por: E Florczak, A Prejbisz, E Szwench-Pietrasz, P Śliwiński, P Bieleń, A Klisiewicz, I Michałowska, E Warchoł, M Januszewicz, M Kała, A Witkowski, A Więcek, K Narkiewicz, V K Somers y A Januszewicz. Journal of Human Hypertension (2013) 27, 678–685.

Recent studies indicate that resistant hypertension (RHTN) is present in about 12% of the treated hypertensive population. However, patients with true RHTN (confirmed out of the office) have not been widely studied.
We prospectively studied 204 patients (123 male, 81female, mean age 48.4 years, range 19–65 years) with truly RHTN (ambulatory daytime mean blood pressure >135/85 mm Hg). We evaluated the frequency of obstructive sleep apnea (OSA), renal artery stenosis (RAS), primary aldosteronism (PA) and other secondary forms of hypertension (HTN) and conditions. Mild, moderate and severe OSA were present in 55 (27.0%), 38 (18.6%) and 54 (26.5%) patients, respectively. Secondary forms of HTN were diagnosed in 49 patients (24.0%), the most frequent being PA (15.7%) and RAS (5.4%). Metabolic syndrome (MS) was present in 65.7% of patients.