The sympathetic nervous system and blood pressure in humans: implications for hypertension

The sympathetic nervous system and blood pressure in humans: implications for hypertension

Por: J P Fisher y J F R Paton. Journal of Human Hypertension (2012) 26, 463–475.

A neurogenic component to primary hypertension (hypertension) is now well established.
Along with raised vasomotor tone and increased cardiac output, the chronic activation of the sympathetic nervous system in hypertension has a diverse range of pathophysiological consequences independent of any increase in blood pressure. This review provides a perspective on the actions and interactions of angiotensin II, inflammation and vascular dysfunction/brain hypoperfusion in the pathogenesis and progression of neurogenic hypertension.