The optimal timing of antihypertensive medication administration for morning hypertension in patients with cerebral infarction

The optimal timing of antihypertensive medication administration for morning hypertension in patients with cerebral infarction

Por: Naohisa Hosomi, Yoshimasa Sueda, Hisashi Masugata, Hiroaki Dobashi, Koji Murao, Masaki Ueno, Takanori Miki, Masakazu Kohno, Akira Nishiyama y Masayasu Matsumoto. Hypertension Research (2012) 35, 720–724.

Morning hypertension is an independent risk factor for cardiovascular diseases, particularly stroke. However, the optimal time at which to take antihypertensive medication to treat morning hypertension remains unclear. We prospectively enrolled elderly patients (over 65 years old) with morning hypertension who had suffered an ischemic stroke (or strokes). Additional treatments (one of six arms) were randomly administered for 10 weeks in the morning, in the evening or at bedtime (n=15 for each time point/medication).