Sex differences in response to angiotensin II receptor blocker-based therapy in elderly, high-risk, hypertensive Japanese patients: a subanalysis of the OSCAR study

Sex differences in response to angiotensin II receptor blocker-based therapy in elderly, high-risk, hypertensive Japanese patients: a subanalysis of the OSCAR study

Por: Kunihiko Matsui, Shokei Kim-Mitsuyama, Hisao Ogawa, Tomio Jinnouchi, Hideaki Jinnouchi y Kikuo Arakawa for the OlmeSartan Calcium Antagonists Randomized (OSCAR) Study Group.  Hypertension Research (2014) 37, 526–532.

Essential hypertension is a common comorbid condition and risk factor for cardiovascular events; in addition to lifestyle modification, drug therapy is the main treatment strategy. Although there are indications for specific classes of antihypertensive drugs for particular patients, such as diuretics for hypertensive African Americans,1 there is no uniform agreement on the type of drug(s) that should be used when physicians choose an antihypertensive drug for newly diagnosed patients without specific indications for those drugs.  Recently, many evidence-based clinical practice guidelines from various clinical fields have been published to improve the quality of patient care.