Antihypertensive drug classes have different effects on short-term blood pressure variability in essential hypertension

Antihypertensive drug classes have different effects on short-term blood pressure variability in essential hypertension

Por: Natacha Levi-Marpillat, Isabelle Macquin-Mavier, Anne-Isabelle Tropeano, Gianfranco Parati y Patrick Maison.  Hypertension Research (2014) 37, 585–590.

Increased blood pressure variability (BPV) contributes to end-organ damage, cardiovascular events and mortality associated with hypertension. In a cohort of 2780 hypertensive patients treated by either calcium channel blockers (CCBs), diuretics, angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs) or ß-blockers alone or in combination, we compared indices of short-term BPV according to the different treatments. Short-term BPV was calculated as the standard deviation (s.d.) of 24?h, daytime or nighttime systolic blood pressure and diastolic blood pressure (SBP and DBP).