10/04/2014

Predictors of plasma and urinary catecholamine levels in normotensive and hypertensive men and women

abr 10th, 2014. En: Propuestas del editor.

Por: A R Saxena, B Chamarthi, G H Williams, P N Hopkins y E W Seely. Journal of Human Hypertension (2014) 28, 292–297.

Age, sex, hypertension and dietary sodium are proposed to affect plasma and urinary catecholamines. Yet no prior study has examined the simultaneous effects of these factors within the same study population. So results may have been confounded by factors not determined. We investigate, for the first time, the impact of simultaneously determined predictors of plasma and urinary catecholamines and the relationship of catecholamines with the diagnosis of hypertension. Hypertensive and normotensive subjects (n=308) were studied off antihypertensives in liberal and low sodium balance. 24?h urinary catecholamines (norepinephrine and epinephrine) were measured. Plasma catecholamines were measured supine after overnight fast.