Effects of resistance training on central blood pressure and wave reflection in obese adults with prehypertension

Por: A.  Figueroa.  Journal of Human Hypertension (2014) 28, 143–144.

Young overweight and obese adults with prehypertension are at increased risk of developing hypertension1 and arterial stiffness (pulse wave velocity, PWV). Moreover, obesity is associated with increased aortic blood pressure (BP) and augmentation index (AIx), two independent predictors of cardiovascular events and all-cause mortality. The increase in aortic systolic BP (SBP) is in part attributed to an increased wave reflection from peripheral arteries to the aorta that causes augmentation of the second systolic peak (P2), leading to a subsequent increase in AIx.

Blood pressure changes after renal denervation at 10 European expert centers

Por: A Persu, Y Jin, M Azizi, M Baelen, S Völz, A Elvan, F Severino, J Rosa, A Adiyaman, F E Fadl Elmula, A Taylor, A Pechère-Bertschi, G Wuerzner, F Jokhaji, T Kahan, J Renkin, M Monge4, P Widimský, L Jacobs, M Burnier, P B Mark, S E Kjeldsen, B Andersson, M Sapoval y J A Staessen, on behalf of the European Network COordinating research on Renal Denervation (ENCOReD).  Journal of Human Hypertension (2014) 28, 150–156.

We did a subject-level meta-analysis of the changes (Δ) in blood pressure (BP) observed 3 and 6 months after renal denervation (RDN) at 10 European centers. Recruited patients (n=109; 46.8% women; mean age 58.2 years) had essential hypertension confirmed by ambulatory BP. From baseline to 6 months, treatment score declined slightly from 4.7 to 4.4 drugs per day. Systolic/diastolic BP fell by 17.6/7.1 mm Hg for office BP, and by 5.9/3.5, 6.2/3.4, and 4.4/2.5 mm Hg for 24-h, daytime and nighttime BP (Pless than or equal to0.03 for all). In 47 patients with 3- and 6-month ambulatory measurements, systolic BP did not change between these two time points (Pgreater than or equal to0.08).