Effects of antihypertensive drugs on central blood pressure: new evidence, more challenges

Effects of antihypertensive drugs on central blood pressure: new evidence, more challenges

Por: Giacomo Pucci, Francesca Battista y Giuseppe Schillaci.  Hypertension Research (2014) 37, 10–12.

βa-blocking drugs have long been used as a first-line therapy for hypertension because of their well-established efficacy in lowering brachial blood pressure (BP) and their long-term favorable effects on all-cause and cardiovascular mortality, as shown in a number of prospective large-scale trials and meta-analyses.  More recently, their use as a preferred strategy for the treatment of essential hypertension has been challenged, as their protective effect on incident stroke may be suboptimal.