10/12/2013

Visit-to-visit systolic blood pressure variability and outcomes in hemodialysis

dic 10th, 2013. En: Propuestas del editor.

Por: T I Chang, J E Flythe, S M Brunelli, P Muntner, T Greene, A K Cheung y G M Chertow. Journal of Human Hypertension (2014) 28, 18–24.

Visit-to-visit blood pressure variability (VTV-BPV) is an independent risk factor for cardiovascular events and death in the general population. We sought to determine the association of VTV-BPV with outcomes in patients on hemodialysis, using data from a National Institutes of Health-sponsored randomized trial (the HEMO study). We used the coefficient of variation (CV) and the average real variability in systolic blood pressure (SBP) as metrics of VTV-BPV. In all, 1844 out of 1846 randomized subjects had at least three visits with SBP measurements and were included in the analysis. Median follow-up was 2.5 years (interquartile range 1.3 –4.3 years), during which time there were 869 deaths from any cause and 408 (adjudicated) cardiovascular deaths.