Cost-Effectiveness of Renin-Guided Treatment of Hypertension

Cost-Effectiveness of Renin-Guided Treatment of Hypertension

Por: Steven M. Smith y Jonathan D. Campbell.  American Journal of Hypertension, volume 26, Issue 11, pp. 1303-1310.

A plasma renin activity (PRA)–guided strategy is more effective than standard care in treating hypertension (HTN). However, its clinical implementation has been slow, presumably due in part to economic concerns. We estimated the cost effectiveness of a PRA-guided treatment strategy compared with standard care in a treated but uncontrolled HTN population. Our results suggest that PRA-guided therapy compared with standard care increases QALYs and medical costs in most scenarios. PRA-guided therapy appears to be most cost effective in younger persons and those with more cardiovascular risk factors.