Resistant hypertension: a practical clinical approach

Resistant hypertension: a practical clinical approach

Por: E S Muxfeldt, F de Souza y G F Salles.  Journal of Human Hypertension (2013) 27, 657–662.

Resistant hypertension (RH) is defined as an uncontrolled office blood pressure (BP) despite the use of at least three antihypertensive drugs. With an increasing prevalence, RH implies in a very high cardiovascular risk and needs a careful clinical approach, aiming to control BP and to reduce its morbidity and mortality. The initial diagnostic approach involves drug adherence checking and the evaluation of antihypertensive scheme, emphasizing the use of diuretics and adequate combination and dosages of the two other drugs, which preferentially reduces cardiovascular risk and promotes prevention/regression of target organ damages.  [Actualizado: 9 de octubre 2013].