Nocturnal urinary melatonin excretion is associated with non-dipper pattern in elderly hypertensives

Nocturnal urinary melatonin excretion is associated with non-dipper pattern in elderly hypertensives

Por: Kenji Obayashi, Keigo Saeki, Junko Iwamoto, Nozomi Okamoto, Kimiko Tomioka, Satoko Nezu, Yoshito Ikada y Norio Kurumatani.  Hypertension Research (2013) 36, 736–740.

Although oral melatonin administration may enhance a nocturnal blood pressure fall, it remains unclear whether endogenous melatonin, which is present at considerably lower levels than pharmacological melatonin, is associated with the non-dipper pattern. The present cross-sectional study aimed to determine the association between urinary melatonin excretion, an index of endogenous melatonin, and the non-dipper pattern. We measured the following variables in 141 elderly hypertensives: overnight urinary melatonin excretion, ambulatory blood pressure and actigraphic physical activity.  [Actualizado: 12 de agosto 2013]