Hypertensive emergencies are associated with elevated markers of inflammation, coagulation, platelet activation and fibrinolysis

Editorial. Estudios importantes sobre hipertension arterial de Cuba y el mundo

Hypertensive emergencies are associated with elevated markers of inflammation, coagulation, platelet activation and fibrinolysis

Por: U Derhaschnig, C Testori, E Riedmueller, S Aschauer, M Wolzt y B Jilma.   Journal of Human Hypertension (2013) 27, 368–373.

Hypertensive crises are frequently observed medical events. They comprise critical elevation of blood pressure (BP) complicated by target organ dysfunction, defined as hypertensive emergency (HE) or without target organ deterioration, that is, hypertensive urgency (HU). Data from in vitro and animal experiments suggest that progressive endothelial damage with subsequent activation of coagulation and inflammation have a key role in hypertensive crisis. However, clinical investigations are scarce. We hypothesized that hypertensive emergencies are associated with enhanced inflammation, endothelial- and coagulation activation. Thus, we enrolled 60 patients admitted to an emergency department in a prospective, cross-sectional study.  [Actualizado: 28 de mayo 2013]