Ethnic differences in the association between blood pressure components and chronic kidney disease in middle aged and older Asian adults

Ethnic differences in the association between blood pressure components and chronic kidney disease in middle aged and older Asian adults

Por: Charumathi Sabanayagam, Boon Wee Teo, E Shyong Tai, Tazeen H Jafar y Tien Yin Wong.  BMC Nephrology 2013, 14:86.

Chronic kidney disease (CKD) is an emerging public health problem worldwide. Previous studies have shown an association between blood pressure (BP) and CKD. However, it is not clear if there are ethnic differences in this association. We examined the association between BP and CKD in a multi-ethnic Asian population in Singapore.
The prevalence of both hypertension and CKD was higher among Malays (68.6, 21%) compared to Chinese (57.9, 5.9%) and Indians (56.0, 7.4%), but treatment for hypertension was lower among Malays (53.4%) compared to Chinese (89.8%) and Indians (83.1%). Hypertension was associated with CKD in all three ethnic groups (OR [95% CI] = 2.71 [1.59-4.63], 2.08 [1.62-2.68], 2.43 [1.66-3.57] in Chinese, Malays and Indians). Among the BP components, both systolic and diastolic BP were associated with CKD in Malays whereas, systolic BP was not significantly associated with CKD, and diastolic BP showed an inverse association which was explained by anti-hypertensive medication use in Chinese and Indians.  [Actuaizado: 02 de mayo 2013]