Rationale, study design, baseline characteristics and blood pressure at 16 weeks in the HONEST Study

A manera de editorial. Los trabajos y opiniones que aquí se exponen son orientadores de lo que se publica en Cuba y en el mundo sobre aspectos relevantes de la hipertensión arterial.

Rationale, study design, baseline characteristics and blood pressure at 16 weeks in the HONEST Study

Por: Ikuo Saito, Kazuomi Kario, Toshio Kushiro, Satoshi Teramukai, Natsuko Zenimura, Katsutoshi Hiramatsu, Fumiaki Kobayashi y Kazuyuki Shimada. Hypertension Research (2013) 36, 177–182.

Large-scale clinical studies have demonstrated that lowering clinic blood pressure (CBP) in hypertensive patients with antihypertensive drug therapy reduces the incidence of cardiovascular (CV) events.
Thus, strict management of blood pressure (BP) is recommended for hypertensive patients in the Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH2009).
Home BP (HBP) measurement has been reported to be more useful than CBP for the appropriate diagnosis, treatment and prediction of future CV events.4–9 HBP measurement is also widely accepted in Japan. Systematic reviews by Stergiou et al.12 and Ward et al.13 confirmed that baseline HBP has a stronger prognostic ability for future CV events compared with CBP; however, few studies have investigated the relationship between on-treatment HBP and CV events in hypertensive patients. (actualizado: 7 de febrero de 2013)